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Isothermal Nucleic Acid Amplification Technology Market by Trends Analysis and Segment Insights to 2028

Loop-mediated isothermal amplification (LAMP) has emerged as a relatively novel and cost-effective DNA amplification alternative to PCR, potentially used by clinicians as a simple screening assay.


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Vinayak Shinde

2 months ago | 3 min read

The global isothermal nucleic acid amplification technology market may exceed USD 2.8 billion by 2028.

The isothermal nucleic acid amplification technology market has gained significant momentum over the last few years, owing to the several advantages of the technology over PCR (polymerase chain reaction). Isothermal amplification procedures require constant temperature and can be performed directly on living cells. They are highly efficient and are extensively used for biosensing targets such as RNA, DNA, cells, small molecules, ions, and proteins. In addition, the increasing technology utilization across bioimaging, biomedicine, and biosensing, coupled with the growing emphasis on effective and precise diagnosis and treatment, will augment the INAAT market share in the future.

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The surging number of diagnostic procedures across the globe owing to the prevalence of chronic and infectious diseases like COVID-19, dengue, HIV, TB, hepatitis, influenza, etc., are likely to propel the isothermal nucleic acid amplification technology market forecast in the coming years. As per the April 2022 facts and figures by WHO, the confirmed COVID-19 cases surpassed 510 million worldwide, resulting in over 6.2 billion deaths. 

The rapid expansion of the global healthcare infrastructure due to the increasing probability of the subsequent waves of the virus outbreak and the ongoing development of breakthrough vaccines to mitigate the crisis will fuel the adoption of advanced nucleic acid amplification techniques globally.

Listed ahead are some prominent trends driving the growth of the isothermal nucleic acid amplification technology industry.

Increasing product demand across North America 

The North America isothermal nucleic acid amplification technology market may undergo significant transformation driven by the improving healthcare infrastructure, increased blood screening procedures, and the expanding patient pool suffering from chronic ailments like cancer, diabetes, and heart diseases.

As per the Pan American Health Organization, over 4 million people were newly diagnosed with cancer in 2020 in the Americas, accounting for nearly 1.4 million deaths. Almost 47% of these deaths and 57% of the cases were diagnosed in people below 69 years. 

These constantly surging numbers, coupled with the increasing incidences of blood transmission and transfusion procedures, will aid the growth of the regional isothermal nucleic acid amplification technology market.

Growing popularity for loop-mediated isothermal amplification

Loop-mediated isothermal amplification (LAMP) has emerged as a relatively novel and cost-effective DNA amplification alternative to PCR, potentially used by clinicians as a simple screening assay. The technique has shown positive outcomes in detecting pathogens in minimally processed samples in the presence of clinical specimen matrices or heat-treated blood.

In May 2022, the government of New Zealand announced the participation of 30 Air New Zealand staff in a clinical trial for LAMP tests for the accurate detection of COVID-19 within 30 minutes using Lucira Check-It test kits. 

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With the precision of a PCR and the speed of a RAT test, the LAMP test is observed as a quick alternative to complex and time-consuming PCR tests for COVID identification. These factors will augment the isothermal nucleic acid amplification technology market outlook in the times to come.

INAAT Reagents to gain considerable traction

The reagents segment is poised to register notable progression, owing to the growing prominence of infectious diseases and the extensive application in fundamental research, assay development, and treatment.

As per the World Health Organization, in 2020, nearly 37 million people were living with HIV, with almost 1.5 million newly acquired cases and over 680,000 deaths due to HIV-related causes.

The rapidly increasing disease burden has proliferated the demand for precise diagnostic procedures to ensure timely and accurate treatment, which, in consequence, will strengthen the isothermal nucleic acid amplification technology market landscape.

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